groES [2017-02-27 15:02:04]

chaperonin, universally conserved protein

locus: BSU06020

pI: 4.00

mw: 10.00 kDa

protein length: 94 aa

gene length: 282 bp

function: protein folding and re-folding

product: chaperonin

essential: yes

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.2|Chaperones/ protein folding]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.4|Heat shock proteins]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue]
• [category|SW 6|Groups of genes] → [category|SW 6.5|Universally conserved proteins]

This gene is a member of the following [SW|regulons]

• [SW|HrcA regulon]

Gene

Coordinates on the chromosome (coding sequence): 649,903 -> 650,187

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Protein family

• groES chaperonin family (according to Swiss-Prot)

Modification

• phosphorylated on Ser-36 [Pubmed|20509597]

Structure

• [PDB|1WE3] ([protein|8F3DEE8828CA6BAAAF6DB2DA4349EF7AA9DF89F8|GroEL]-[protein|0D8B3F1F86FDBAE0F3B3651F456340F147B394AF|GroES] complex from ''Thermus thermophilus'', 65% identity) [Pubmed|15296740]

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Additional information

• [SW|universally conserved protein]

Expression and Regulation: [[this]]

Labs working on this gene/protein

• [SW|Wolfgang Schumann], Bayreuth University, Germany [http://www.genetik.uni-bayreuth.de/LSGenetik1/schumann_research.htm Homepage]

References

• 1350777,1350776,8576042,7592421,20509597,15378759,15296740,27184767